Alisa Kanganis
AP Biology
January 31, 2019
Current Event 15
Wright, Jessica. “Genetic Tests for Autism Can Sometimes Change Lives.” Scientific American, 31 Jan. 2019,
For years, Angela questioned if her son was developing normally. Her son, James, was not able to sit up on his own until he was 1 or crawl until he was 18 months old. He was also struggling to breath and could not sleep for periods longer than 20 minutes, but doctors assured her that he was fine. However, when James was four, he was finally diagnosed with autism. Up to this point, James had had five nasal surgeries, the first of which resulted in a complication due to his abnormally low platelet count. He had to be rushed back to the hospital in an ambulance after having a nosebleed that his mother referred to as looking like “someone had been killed in his bed”. This all could have been avoided if genetic testing for autism was available at the time that James was born. Years later, when this testing surfaced, Angela discovered that James had a mutation in the TAF1 gene, which explains his autism and developmental delay; and one in the gene GP9 that causes his low platelet count and led to the complications after surgery. While this screening is expensive, it is slowly becoming more and more affordable, hopefully to the point where it is accessible to all children who appear to be experiencing developmental delays or autism. Clearly, as with James’ case, receiving testing can prevent unexpected complications and have extremely beneficial effects on a child’s development as a whole since the physiological areas impacted by the mutation(s) can be identified.
These recent advancements in genetic screening have a monumental impact on society. According to the CDC, 1 in 6 children have developmental delays and 1 in 59 have autism, so there is obviously a large amount of people who could benefit from this. While it is not a cure, it can help people identify the treatments needed to manage their issues.
This article was not only informative, but very impactful. By following James early life, I was able to understand just how much this genetic testing could have influenced him. Furthermore,the author is very detailed and gives a good description of the accessibility and results of the screening. However, the article does lack an explanation as to how exactly genetic screening works. If the author included this, the article would be very well-rounded and include all the information a person with no background in biology would need to fully understand it.